Page 248 - 北京京煤集团总医院第十届·2022学术年会论文集

北京京煤集团总医院 第十届·2022 学术年会论文集

mellitus were divided into coronary artery calcification group and control group according to the

coronary artery calcification score. The general clinical baseline datum，such as age，and so on，

were recorded．Biochemical indexes：blood glucose，blood lipids，calcium，phosphorus， alkaline
phosphatase(ALP)，molecular fragment of osteocalcin N terminal(N-MID)，type I collagen carboxyl

end peptide crosslinking(β-CTX) and other biochemical indicators were detected. Meanwhile, bone
mineral density (BMD) and bone metabolism related indexes were examined to explore the

correlation between BMD, bone metabolism related indexes and coronary artery calcification and

other indexes. Results：There was no significant difference in bone mineral density and bone

metabolism between the coronary artery calcification group and the control group (P>0.05).Bone

mineral density in patients with coronary artery calcification was correlated with height, weight,

creatinine, uric acid, blood phosphorus, 25(OH)D3, β-CTX, PTH, TL1-4, T-T, smoking and

drinking (P<0.05). Coronary heart disease was correlated with BMDL1-4 (P<0.05), menopausal

years were correlated with BMDL2-4, age, menopausal years, waist circumference, hip

circumference, systolic blood pressure, HDL-C, HOMA-IS, urea nitrogen were correlated with

femoral neck bone mineral density (P<0.05). Age, menopausal years, hip circumference, systolic

blood pressure, HDL-C, INS, HOMA-IS and CRP were correlated with total hip BMD (P<0.05).
The menopausal years, TL1-4, coronary artery stenosis, coronary heart disease, coronary

atherosclerosis and fatty liver were correlated with BMD-L1-4 and BMD-L2-4 (P<0.05). The
presence of coronary artery stenosis and coronary atherosclerosis were correlated with BMD-L1-4

(P<0.05). Age, body weight, systolic blood pressure, HDL-C, calcium, GSP, PTH, T-T were

correlated with femoral neck BMD (P<0.05). Age, height, weight, PTH, T-T and fatty liver were

correlated with total hip BMD (P<0.05). Logistic regression analysis showed that coronary artery

calcification was correlated with age, waist circumference, albumin, coronary heart disease,

coronary atherosclerosis and coronary artery stenosis (P<0.05). There were correlations between

coronary artery stenosis and waist circumference, systolic blood pressure, menopausal years, blood

phosphorus level, coronary artery calcification and coronary heart disease (P<0.05). Conclusion：

There was no significant correlation between coronary artery calcification score and BMD and bone

metabolism related indexes in type 2 diabetic patients, but BMD in diabetic patients with coronary

artery calcification was correlated with age, height, obesity, menopausal years, creatinine, uric acid,

coronary heart disease and blood pressure. Age, height, obesity, menopausal years, blood calcium,

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