Page 215 - 北京京煤集团总医院第十届·2022学术年会论文集

北京京煤集团总医院 第十届·2022 学术年会论文集

无创正压通气治疗中氧气注入方式对煤工尘肺合并呼吸衰

竭患者呼吸生理的影响

张建红，化静，余春晓，李瑶（北京京煤集团总医院呼吸与危重症医学科）
【摘要】目的：探讨煤工尘肺合并呼吸衰竭患者在无创正压通气过程中不同氧气注入方式

对其呼吸生理的影响。方法：收集 2018 年 01 月至 2020 年 01 月期间收治的 60 例煤工尘
肺合并呼吸衰竭患者，进行随机分为观察组、对照组，观察组在鼻导管吸氧的基础上，给

予无创正压呼吸机辅助通气，对照组氧气注入点位于无创呼吸机面罩上。比较两组患者机

械通气 120 分钟治疗后的 pH 值、动脉血氧分压( PaO2) 、动脉血二氧化碳分压( PaCO2)等

呼吸生理指标。结果：经 120 分钟不同氧气注入方式的无创正压通气后鼻导管组治疗前后

比较 pH 值、PaCO2 、PaO2 、ACHEⅡP 值<0.05，与对照组 pH 值、PaCO2 、ACHEⅡ比较

P 值>0.05,差异无统计学意义，两组间 PaO2 比较 P 值<0.05（t 值=4.151，P 值=0.001），

差异有显著统计学意义。结论：在鼻导管吸氧的基础上，给予无创正压呼吸机辅助通气治

疗煤工尘肺合并呼吸衰竭病人可以改善 pH 值、PaCO2 、PaO2 、ACHEⅡ，较氧气注入点

位于无创面罩的无创正压通气可以更好的改善缺氧。

【关键词】无创正压通气；氧气注入位点；煤工尘肺；鼻导管；呼吸衰竭

Effect of oxygen injection on respiratory physiology of coal worker's pneumoconiosis
patients with respiratory failure during noninvasive positive pressure ventilation

Jianhong Zhang, Jing Hua，Chunxiao Yu，Yao Li
Abstract Objective To investigate the effects of different oxygen injection modes on respiratory

physiology of coal worker's pneumoconiosis patients with respiratory failure during noninvasive

positive pressure ventilation. Methods 60 cases of coal worker's pneumoconiosis with respiratory

failure from January 2016 to June 2017 were randomly divided into observation group and control

group. On the basis of nasal tube oxygen inhalation, the observation group was given non-invasive

positive pressure ventilator-assisted ventilation. The oxygen injection site of the control group was

located on the non-invasive ventilator mask. Physiological indicators such as pH value, arterial

partial pressure of oxygen (PaO 2) and arterial partial pressure of carbon dioxide (PaCO 2) were

compared between the two groups after 120 minutes of mechanical ventilation. Results After 120

minutes of non-invasive positive pressure ventilation with different oxygen injection modes, the

values of pH, PaCO 2, PaO 2 and ACHE II P in nasal catheter group before and after treatment

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