Page 246 - 北京京煤集团总医院第十一届·2023学术年会论文集

北京京煤集团总医院 第十一届·2023 学术年会论文集

177 例脂溢性角化病临床病理分析

邓桂霞，杜桂清，王秋红，邵林娟，田森，乔婷婷（北京京煤集团总医院病理科，北京 102300）

【摘要】目的：探讨脂溢性角化病临床、病理特征。方法：回顾 177 例经组织病理学诊断为

脂溢性角化病患者的病理资料，分析其临床及病理特征。 结果：本组 177 例脂溢性角化病，
发病年龄 50 岁及以上者 141 例 （ 79.7%）；皮损多见于头颈面部 101 例 （ 57.1%）、躯干 56 例

（31.6%）；病理类型中棘层肥厚型 97 例 （ 54.8%），角化过度型 38 例（21.5%）； 177 例患者

中 137 例（77%）临床与病理诊断一致，临床误诊为寻常疣 21 例（11.7%），色素痣 15 例

（8.3%）； 177 例患者中有 12 例（6.8%）合并其它恶性肿瘤。结论：脂溢性角化病的发病率

与年龄呈正相关；皮肤暴露区域明显高于非暴露区域；病理类型以棘层肥厚型最多见；本病

容易误诊为寻常疣、色素痣，组织病理检查在诊断及鉴别诊断中具有重要作用；也有合并恶

性肿瘤的可能，随着年龄的增加恶性肿瘤发病率增高。

【关键词】脂溢性角化病；临床；病理 ；鉴别诊断；恶性肿瘤；

[Abstract] Obejective：To axplore the clinical and pathological features of seborrheic keratosis

(SK). Methods ： The review the pathological date of 177 cases of SK diagnosed by

histopatholology, and analyze their clinical and pathological features. Results：There were 177

cases of SK in this group, of which 141 were aged 50 years or above(79.7%); Skin lesions were

more common in head ,neck and face in 101 cases(57.1%), and in body in 56 cases(31.6%);Among
the pathological types, there were 97 cases(54.8%)of hypertrophic spinous layer and 38

cases(21.5%)of hyperkeratosis; Of 177 patients,137(77%)were diagnosed as common by clinical

and pathological diagnosis, and were misdiagnosed as commom; there were 21 cases of verruca

vulgaris (11.7%) and 15 cases of pigmented nevus(8.3%); Among 177 patients with SK,12 patients

were complicated with Other malignant tumors. Conclusion：The incidence of SK is positively

correlated with age, and the skin exposure area is significantly higher than that of non-exposed area.

The most commom pathological type was hypertrophic spinous layer; SK is easily misdiagnosed as

verruca vulgaris , pigmented nevus; Histopathological examination plays an important role in

diagnosis and differential diagnosis; SK also has the possibility of complicated with malignant

tumor, and the incidence of malignant tumor increases with age.

[Key words] seborrheic keratosis ; clinical; pathology; differential diagnosis;malignant tumor;

脂溢性角化病（seborrheic keratosis SK）又名老年疣、基底细胞乳头状瘤，是一种多发

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