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北京京煤集团总医院                                              第十届·2022 学术年会论文集


                   3.3.  Construction of TF-gene, miRNA-gene interaction networks

                       From the NetworkAnalyst website, the TFs and miRNAs of overlapping DEGs were predicted,

                   65 TFs and 369 miRNAs were obtained, and TF-DEG and miRNA-DEG interaction networks were
                   constructed. In the TF–DEG interaction network, FOXC1 and GATA2 were regulated by many


                   DEGs (Figure 5A), and hsa-miR-93-5p and hsa-miR-17-5p interacted with numerous DEGs (Figure
                   5B).



































































                   Figure 5. Construction of TFs-gene, miRNAs-gene interaction network. A: TF–DEG interaction


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