Page 127 - 北京京煤集团总医院第十届·2022学术年会论文集
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北京京煤集团总医院 第十届·2022 学术年会论文集
CONUT评分对老年脓毒症患者短期预后的预测价值分析
王娇,武日茹,提俊响(1.北京京煤集团总医院急诊科;2.徐州市中心医院ICU)
【摘要】目的:探讨控制营养状况(CONUT)评分对老年脓毒症患者短期预后的预测价值。方
法:回顾性分析 240 例老年脓毒症患者的临床资料,收集患者的性别、年龄、吸烟史、饮酒
史、合并症、感染灶等一般资料,以及血培养阳性情况、急性生理与慢性健康评分表
(APACHEⅡ)评分、序贯器官衰竭估计评分(SOFA)评分、CONUT 评分、急性肾损伤(AKI)发
生情况、脓毒症休克情况、气管插管情况、入院第 24 小时血乳酸(LAC)水平、诊断脓毒症至
入急诊重症加强护理病房(ICU)时间。分析影响患者短期预后的危险因素。结果:死亡患者
年龄(75.19±4.27)岁、APACHEⅡ评分(25.26±5.15)分、SOFA 评分[9(7,12)]分、CONUT 评分
[4(3,6)]分、急性肾损伤(AKI)发生率 58.0%、脓毒症休克发生率 55.0%、气管插管率 45.0%、
入院第 24 小时 LAC[2.22(1.07,2.92)]mmol/L 均高于存活患者的(72.89±4.47)岁、(20.42±5.71)
分、[8(5,10)]分、[3(2,4)]分、37.1%、33.6%、30.0%、[1.75(0.87,2.65)]mmol/L,差异均
有统计学意义(P<0.05)。将单因素分析中 P<0.05 的指标引入 Logistic 回归模型中,采用
Forward: LR 法筛选变量,在排除混杂因素的影响后,多变量分析结果显示,年龄、APACHEⅡ
评分、SOFA 评分、CONUT 评分、AKI 均为脓毒症患者 28 d 死亡的危险因素(P<0.05)。结
论:除 APACHEⅡ、年龄、SOFA 评分、AKI 发生率等是预测入院老年脓毒症患者的预后指
标外,CONUT 评分也是预测老年脓毒症预后的一个实用指标,营养不良对脓毒症患者预后
产生负面影响可能包括免疫改变、炎症通路等多方面因素。
【关键词】脓毒症;控制营养状况;营养不良;老年患者;短期预后
Predictive value of CONUT score for short-term prognosis in elderly patients with sepsis
Abstract Objective:To discuss the predictive value of CONUT score for short-term prognosis in
elderly patients with sepsis. Methods:The clinical data of 240 elderly patients with sepsis were
retrospectively analyzed,and general information such as gender,age,history of smoking,history
of alcohol consumption,comorbidities,foci of infection were collected,as well as positive blood
cultures,Acute Physiology and Chronic Health Scale (APACHE Ⅱ) scores,Sequential organ failure
assessment (SOFA) scores,controlling nutritional status (CONUT) scores,acute kidney injury
(AKI) occurrence,septic shock,tracheal intubation,blood lactate (LAC) level at 24 h after
admission,and time from diagnosis of sepsis to admission to the acute intensive care unit (ICU).
The risk factors for short-term prognosis of patients were analyzed. Results:The dead patients had
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