Page 267 - 北京京煤集团总医院第十一届·2023学术年会论文集

北京京煤集团总医院 第十一届·2023 学术年会论文集

药师参与抗凝服务对华法林抗凝治疗质量的效果评价

陶丽源，白沁宜，靳佳，段蕊，刘建平 （北京京煤集团总医院药剂科，北京 102300）
*
基金项目：北京京煤集团总医院院级科研基金项目（2021-10） *通讯作者：刘建平
【摘要】目的：建立符合我院实际情况的华法林抗凝药学服务模式，并对该模式进行效果评

估。方法：对 2020 年 1 月至 2022 年 12 月在我院住院期间服用华法林且出院后继续服用华
法林的患者作为研究对象，将是否接受全程化的药学服务分为研究组和对照组，以目标范围

时间比（time in the therapeutic range,TTR)达标率为目标值，评估两组华法林的抗凝治疗质量。
结果：研究最终纳入 41 例，其中对照组 19 例，研究组 22 例。患者人口统计学资料及临床

情况基线特征：年龄、性别比例 、抗凝适应症、服用时间、出院带药种类数、肝肾功能等

指标两组间无显著差异（P＞0.05）。研究组和对照组的抗凝治疗质量达标率分别为：72.73%
和 26.32%，研究组的抗凝治疗质量达标率显著高于对照组（P＜0.05）。结论：我院建立的

华法林抗凝药学服务模式，可以提高华法林抗凝质量，也利于一线药师药学服务转型，值得
借鉴和推广。

【关键词】华法林；药师；药学服务；抗凝质量
Evaluation of the effect of pharmacists participating in anticoagulation service on the
quality of warfarin anticoagulation treatment

Tao Liyuan，Bai Qinyi，Jin Jia，Duan Rui，Liu Jianping *
（Department of Pharmacy，Beijing Jingmei Group General Hospital，Beijing102300, China)

[Abstract] Objective：To establish a warfarin anticoagulant pharmaceutical service model in line
with the actual situation of our hospital, and evaluate the effect. Methods：The patients who took

warfarin during hospitalization in our hospital from January 2020 to December 2022 and continued
to take warfarin after discharge were taken as the study subjects. They were divided into study group
and control group according to whether they accepted the whole-process pharmaceutical service,

evaluating the quality of anticoagulant therapy with time in the therapeutic range (TTR). Results：
41 cases were included in the study, 19 cases in the control group and 22 cases in the study group.
There was no significant difference between the two groups in terms of demographic data and

baseline characteristics of clinical conditions: age, sex ratio, anticoagulation indications, taking time,
number of types of drugs taken after discharge, liver and kidney function (P>0.05). The rate of
reaching the standard of anticoagulation treatment quality in the study group and the control group

was 72.73% and 26.32%, respectively. The rate of reaching the standard of anticoagulation
treatment quality in the study group was significantly higher than that in the control group (P＜
0.05）. Conclusions：Pharmacists participating in the whole-process anticoagulant pharmaceutical

service mode can improve the anticoagulant quality of warfarin, which is worthy of reference and
promotion.

[Key words] Warfarin；Pharmacist；Pharmaceutical service； Quality of anticoagulation therapy

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