Page 7 - 北京京煤集团总医院第十届·2022学术年会论文集

北京京煤集团总医院 第十届·2022 学术年会论文集

[3]
analgesic and sedative gastroscopy limited its widespread development in primary hospitals .
The application of sedatives and analgesics can effectively narrow the discomfort during

gastroscopy. However, the inhibitory effect of narcotic drugs on the cardiovascular system can
result in hypotension and even coma. Some subjects have adverse reactions such as nausea and

vomiting after examination. Some scholars have found that many subjects did not choose sedative
[4]
and analgesic gastroscopy for the fear of adverse reactions related to anesthesia , so there is still
a high objective demand for non-analgesic and sedative gastroscopy in the examined population.

This study observed and compared the application effects of nasal breathing and nasal inspiration

and oral expiration in non-analgesic sedative gastroscopy, and discussed the safety, tolerance and

comfort of the two breathing methods.

1 Materials and methods

1.1 General information

This prospective cohort study was performed at the Gastrointestinal Endoscopy Center, Beijing

Jingmei Group General Hospital. The study was endorsed by the Ethics Committee of Beijing

Jingmei Group General Hospital (No. 2020KY018-01) and informed consent was obtained from all
patients. A total of 60 subjects who underwent non-analgesic and sedative gastroscopy in the

Gastrointestinal Endoscopy Center of Beijing Jingmei Group General Hospital from January 2021
to June 2021 were selected as the research subjects. The subjects were divided into 2 groups

according to their wishes: the nasal breathing group (group A, n=30) and the nasal inhalation and

mouth expiration group (group B, n=30). There were 28 males and 32 females, aged 18 to 78 years

old, with an average of 50.87 years old, and body mass index (BMI) of 17.69 to 32.46. The P values

of the two groups in terms of age and BMI were all greater than 0.05, and the difference was not

statistically significant (see Table 1). Inclusion criteria: (1) Those who with smooth nasal

breathing; (2) Those who with no contraindications for gastroscopy; (3) Those who informed

consent and voluntary participation in the study. Exclusion criteria: (1) Those who with

nasopharynx or oropharyngeal airway obstruction; (2)Those who have contraindications to

gastroscopy, such as serious cardiovascular diseases accompanied by cardiac insufficiency or

serious coronary heart disease, descending aortic aneurysm, serious lung diseases, serious oral or

throat diseases, endoscopy failure, acute tonsillitis, acute pharyngitis, corrosive esophagitis,

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