Page 192 - 北京京煤集团总医院第十一届·2023学术年会论文集

北京京煤集团总医院 第十一届·2023 学术年会论文集

infection rates of the control group, colorectal polyps group and colorectal cancer group were 20.8%
(37/178)，23.0% (467/2034) and 27.1% (32/118)，respectively, and the differences were statistically

significant (all P > 0.05). Among 2 034 cases of colorectal polyps, there were 612 cases of
inflammatory polyps, 371 cases of proliferative polyps and 1 051 cases of adenomatous polyps. The
infection rates of Hp in the three kinds of colorectal polyps were 24.5% (150/612), 22.4% (83/371)

and 22.3% (234/1051), respectively. The proportion of patients with gastric polyps was 34.6%
(212/612), 38.3% (142/371) and 39.3% (413/1051), respectively, and the differences were
statistically significant (all P>0.05). The age of the three colorectal polyps groups was significantly
different from that of the control group and colorectal cancer group (all P<0.05) except for

inflammatory polyps and proliferative polyps groups. The proportion of female in three kinds of
colorectal polyps combined with gastric polyps was higher than that in male patients (all P<0.05).
The age of Hp positive patients in the control group, different types of colorectal polyps groups and
colorectal cancer group was lower than that in negative patients, but there was a statistically

significant difference only in adenomatous polyps group (P=0.002). The age of patients with
different types of colorectal polyps combined with gastric polyps was older than that of those
without gastric polyps, and the age of patients with colorectal cancer combined with gastric polyps

was younger than that of those without gastric polyps (all P<0.05). There was no assocaiton of Hp
infection and gastric polyps with colorectal polyps and colorectal cancer (all P>0.05). Conclusions
Hp infection may promote the early occurrence of colorectal adenomatous polyps. There is no
evidence that gastric polyps are associated with the risk of colorectal polyps. Female patients with

colorectal polyps have a higher risk of gastric polyps.
【Key words】 Colorectal neoplasms; Colorectal polyps; Helicobacter pylori; Gastric polyps

2018 年中国癌症统计报告显示，我国结直肠癌的发病率、病死率在恶性肿瘤中分别位
[1]
居第3、5 位 。结直肠息肉主要病理类型有炎性息肉、增生性息肉、腺瘤性息肉，大部分结
直肠癌被认为起源结直肠腺瘤性息肉 [2⁃3] 。近年来胃肠道息肉的检出率逐年升高，呈现出发
[5]
病普遍化、年轻化、易复发、难预防的趋势，患病率随着年龄的增长而升高 。有研究表明，
结直肠癌、结直肠腺瘤性息肉的发病可能与幽门螺杆菌（Hp）感染有关 [5⁃6] 。但关于胃息肉
对肠息肉的影响，各研究结果尚不一致 [7⁃8] 。本研究探讨结直肠息肉、结直肠癌患者Hp 感染

及合并胃息肉情况，希望为临床治疗提供依据。
1. 资料与方法

1.1 一般资料

纳入标准：行胃镜及肠镜检查，胃镜取活组织检查，同时肠镜下发现息肉取活组织检查
的患者；排除标准：（1）炎症性肠病、遗传性息肉病患者；（2）胃镜检查发现消化性溃疡、

胃部肿瘤患者；（3）2 周内行Hp根除治疗的患者。回顾性分析2020 年1 月至2021 年 6 月
我院胃镜及肠镜检查发现的2 034 例结直肠息肉患者及118 例结直肠癌患者的临床资料，结

直肠息肉患者中男性960 例，女性1074 例，年龄（56±11）岁；结直肠癌患者中男性77 例，

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